Motif ID: FOX{C1,C2}.p2

Z-value: 1.179


Transcription factors associated with FOX{C1,C2}.p2:

Gene SymbolEntrez IDGene Name
FOXC1 2296 forkhead box C1
FOXC2 2303 forkhead box C2 (MFH-1, mesenchyme forkhead 1)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
FOXC1chr6_+_1555679-0.136.2e-01Click!
FOXC2chr16_+_851583570.039.2e-01Click!


Activity profile for motif FOX{C1,C2}.p2.

activity profile for motif FOX{C1,C2}.p2


Sorted Z-values histogram for motif FOX{C1,C2}.p2

Sorted Z-values for motif FOX{C1,C2}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOX{C1,C2}.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_74491272 5.401 ALB
albumin
chr17_-_61655915 5.319 NM_000042
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr9_-_74735669 4.988 ALDH1A1
aldehyde dehydrogenase 1 family, member A1
chr4_+_74500748 4.826 ALB
albumin
chr3_+_134978615 4.734 TF
transferrin
chr3_-_150578023 4.429 TM4SF1
transmembrane 4 L six family member 1
chr10_+_7785347 4.068 ITIH2
inter-alpha (globulin) inhibitor H2
chr3_-_150578103 3.985 TM4SF1
transmembrane 4 L six family member 1
chr10_+_7785360 3.782 ITIH2
inter-alpha (globulin) inhibitor H2
chr10_+_7785331 3.710 ITIH2
inter-alpha (globulin) inhibitor H2
chr10_+_7785290 3.356 ITIH2
inter-alpha (globulin) inhibitor H2
chr14_+_94117511 3.337 SERPINA5
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
chr3_-_150578148 2.965 TM4SF1
transmembrane 4 L six family member 1
chr14_+_94117483 2.956 NM_000624
SERPINA5
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
chr10_+_7785235 2.830 NM_002216
ITIH2
inter-alpha (globulin) inhibitor H2
chr11_-_2113297 2.738 IGF2
insulin-like growth factor 2 (somatomedin A)
chr1_-_56750235 2.642 PPAP2B
phosphatidic acid phosphatase type 2B
chr3_-_115826481 2.620 NM_001164346
ZBTB20
zinc finger and BTB domain containing 20
chr2_-_188127294 2.284 TFPI
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr2_+_189547377 2.102 COL3A1
collagen, type III, alpha 1
chr2_+_189547358 2.045 COL3A1
collagen, type III, alpha 1
chr2_+_189547323 1.985 NM_000090
COL3A1
collagen, type III, alpha 1
chr17_-_7023378 1.778 NM_001197216
NM_001671
ASGR1

asialoglycoprotein receptor 1

chr12_+_99391870 1.702 NR1H4
nuclear receptor subfamily 1, group H, member 4
chr12_+_99391681 1.601 NM_005123
NR1H4
nuclear receptor subfamily 1, group H, member 4
chr17_-_7023283 1.509 ASGR1
asialoglycoprotein receptor 1
chr2_-_88208650 1.450 NM_001443
FABP1
fatty acid binding protein 1, liver
chr4_-_84254912 1.442 PLAC8
placenta-specific 8
chr4_-_100359353 1.357 NM_000672
NM_001102470
ADH6

alcohol dehydrogenase 6 (class V)

chr20_+_42644633 1.355 PKIG
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
chr6_+_158358067 1.215 NM_001178088
SYNJ2
synaptojanin 2
chr14_+_94117545 1.209 SERPINA5
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
chr4_-_84254932 1.142 NM_001130715
NM_016619
PLAC8

placenta-specific 8

chr21_-_42608531 1.115 TFF3
trefoil factor 3 (intestinal)
chr2_-_188127430 1.098 NM_001032281
NM_006287
TFPI

tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)

chr4_-_84254873 1.073 PLAC8
placenta-specific 8
chr9_+_123088217 1.055 GSN
gelsolin
chr3_-_116272911 1.018 NM_001164343
ZBTB20
zinc finger and BTB domain containing 20
chr19_-_6671585 0.914 NM_000064
C3
complement component 3
chrX_-_130250880 0.891 IGSF1
immunoglobulin superfamily, member 1
chr1_+_151867483 0.814 NM_006271
S100A1
S100 calcium binding protein A1
chr3_-_150578207 0.814 NM_014220
TM4SF1
transmembrane 4 L six family member 1
chr17_-_36347197 0.812 NM_015515
KRT23
keratin 23 (histone deacetylase inducible)
chr19_+_8415875 0.804 HNRNPM
heterogeneous nuclear ribonucleoprotein M
chr2_-_216008689 0.784 FN1
fibronectin 1
chr4_+_166519392 0.752 NM_001873
CPE
carboxypeptidase E
chr7_+_94123672 0.726 PEG10
paternally expressed 10
chr19_-_47723183 0.705 CEACAM1
carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
chr16_+_68238460 0.703 NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr7_+_134483305 0.649 NM_018295
TMEM140
transmembrane protein 140
chr14_-_93924663 0.632 SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr14_-_93924873 0.623 NM_000295
SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr8_-_13018123 0.619 NM_001164271
DLC1
deleted in liver cancer 1
chr14_+_99601498 0.608 NM_016337
EVL
Enah/Vasp-like
chr14_+_99601517 0.603 EVL
Enah/Vasp-like
chr5_+_35892747 0.552 NM_002185
IL7R
interleukin 7 receptor
chr20_+_9146036 0.540 NM_182797
PLCB4
phospholipase C, beta 4
chrX_-_130251068 0.535 NM_001170961
NM_001170962
NM_001555
NM_205833
IGSF1



immunoglobulin superfamily, member 1



chr20_+_56904042 0.532 GNAS
GNAS complex locus
chr15_-_88150823 0.530 ANPEP
alanyl (membrane) aminopeptidase
chr9_-_114520184 0.529 NM_021218
C9orf80
chromosome 9 open reading frame 80
chr8_-_17599438 0.496 NM_020749
MTUS1
microtubule associated tumor suppressor 1
chr13_+_96592051 0.467 MBNL2
muscleblind-like 2 (Drosophila)
chr11_-_74818685 0.451 KLHL35
kelch-like 35 (Drosophila)
chr16_+_80626456 0.450 HSD17B2
hydroxysteroid (17-beta) dehydrogenase 2
chr4_-_3503881 0.450 LRPAP1
low density lipoprotein receptor-related protein associated protein 1
chr21_-_42608774 0.443 NM_003226
TFF3
trefoil factor 3 (intestinal)
chr22_+_38246509 0.439 NM_001675
NM_182810
ATF4

activating transcription factor 4 (tax-responsive enhancer element B67)

chr10_-_82039158 0.436 NM_000429
MAT1A
methionine adenosyltransferase I, alpha
chr17_+_70984173 0.412 KIAA0195
KIAA0195
chr21_-_42689192 0.403 NM_024022
NM_032405
TMPRSS3

transmembrane protease, serine 3

chr17_+_7563763 0.396 NM_020877
DNAH2
dynein, axonemal, heavy chain 2
chr8_-_11742668 0.395


chr7_-_50596238 0.393 NM_000790
DDC
dopa decarboxylase (aromatic L-amino acid decarboxylase)
chr11_-_8789457 0.381 NM_139157
ST5
suppression of tumorigenicity 5
chr17_+_37967690 0.375 COASY
CoA synthase
chr5_-_111121150 0.364 NM_001142479
NM_001142480
NM_001142478
C5orf13


chromosome 5 open reading frame 13


chr11_+_111288686 0.355 HSPB2-C11ORF52
HSPB2
HSPB2-C11orf52 read-through transcript
heat shock 27kDa protein 2
chr16_+_68157611 0.352 NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr2_-_190635566 0.349 NM_005259
MSTN
myostatin
chrX_+_70438352 0.349 NM_012278
ITGB1BP2
integrin beta 1 binding protein (melusin) 2
chr14_+_75141557 0.344 NM_001195283
FLVCR2
feline leukemia virus subgroup C cellular receptor family, member 2
chrX_-_40391744 0.343 NM_144970
CXorf38
chromosome X open reading frame 38
chr11_+_1817294 0.343 NM_001145829
TNNI2
troponin I type 2 (skeletal, fast)
chr17_+_37967617 0.340 NM_001042529
NM_001042530
NM_001042531
NM_001042532
NM_025233
COASY




CoA synthase




chr2_-_174968595 0.339 NM_004882
CIR1
corepressor interacting with RBPJ, 1
chr17_+_46176105 0.339 LUC7L3
LUC7-like 3 (S. cerevisiae)
chr16_+_14835214 0.331 NOMO1
NODAL modulator 1
chr7_+_94123612 0.329 NM_001172437
NM_001172438
PEG10

paternally expressed 10

chr14_-_23846904 0.324 CIDEB
cell death-inducing DFFA-like effector b
chr3_-_52688768 0.321 NM_018165
NM_181042
PBRM1

polybromo 1

chr13_-_19244398 0.321 PSPC1
paraspeckle component 1
chr11_+_111288669 0.317 NM_001541
HSPB2-C11ORF52
HSPB2
HSPB2-C11orf52 read-through transcript
heat shock 27kDa protein 2
chr8_-_11739592 0.312 CTSB
cathepsin B
chr7_-_55897938 0.307 NM_207366
SEPT14
septin 14
chrX_+_68752635 0.303 NM_001005609
NM_001005610
NM_001005612
NM_001005613
NM_001399
EDA




ectodysplasin A




chr6_-_138862273 0.298


chr2_+_69055208 0.296 NM_019617
GKN1
gastrokine 1
chr17_+_37967702 0.291 COASY
CoA synthase
chr9_-_130683997 0.276 NM_001122671
NM_001122672
NM_004059
CCBL1


cysteine conjugate-beta lyase, cytoplasmic


chr9_+_133295297 0.272 NM_013318
PRRC2B
proline-rich coiled-coil 2B
chr8_+_70541412 0.269 NM_001128204
NM_015170
SULF1

sulfatase 1

chr9_+_123088690 0.266 GSN
gelsolin
chr4_-_3503951 0.264 NM_002337
LRPAP1
low density lipoprotein receptor-related protein associated protein 1
chr4_+_38740246 0.261 NM_015990
NM_199039
KLHL5

kelch-like 5 (Drosophila)

chr1_+_200246370 0.256 ELF3
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr17_+_70964258 0.253 NM_014738
KIAA0195
KIAA0195
chr9_-_135922912 0.253 NM_007371
BRD3
bromodomain containing 3
chr1_-_36721010 0.249 CSF3R
colony stimulating factor 3 receptor (granulocyte)
chr10_-_7722747 0.247 ITIH5
inter-alpha (globulin) inhibitor H5
chr4_-_90197140 0.240 NM_014883
FAM13A
family with sequence similarity 13, member A
chr10_-_112668892 0.239 NM_001195304
NM_001195305
NM_001195307
BBIP1


BBSome interacting protein 1


chr10_-_98315090 0.238 TM9SF3
transmembrane 9 superfamily member 3
chr22_+_29333069 0.237 NM_000355
NM_001184726
TCN2

transcobalamin II

chr10_+_90414125 0.235 NM_001198828
NM_001198829
NM_001198830
NM_004190
LIPF



lipase, gastric



chr17_-_36346240 0.235 KRT23
keratin 23 (histone deacetylase inducible)
chr6_-_133076873 0.233 NM_004666
VNN1
vanin 1
chr4_+_120276386 0.228 NM_016599
MYOZ2
myozenin 2
chr16_+_29739256 0.227 MVP
major vault protein
chr2_+_27109341 0.224 TMEM214
transmembrane protein 214
chr20_+_56903595 0.224 GNAS
GNAS complex locus
chr16_-_74024750 0.223 NM_006324
CFDP1
craniofacial development protein 1
chr11_+_113672407 0.223 NNMT
nicotinamide N-methyltransferase
chr16_+_29739215 0.222 NM_005115
NM_017458
MVP

major vault protein

chr1_-_120413542 0.212 NOTCH2
notch 2
chr3_-_95175282 0.209 PROS1
protein S (alpha)
chr5_+_150000394 0.205 NM_001109974
NM_007286
SYNPO

synaptopodin

chr21_-_26345294 0.202


chr2_-_224612177 0.199 NM_001136528
NM_006216
SERPINE2

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2

chrX_-_40391610 0.197 CXorf38
chromosome X open reading frame 38
chr1_-_201422533 0.196 NM_001276
CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr5_-_39460787 0.196 DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr11_+_113672378 0.191 NNMT
nicotinamide N-methyltransferase
chr5_-_39460687 0.188 DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr10_-_91092410 0.184 LIPA
lipase A, lysosomal acid, cholesterol esterase
chr2_-_88066423 0.181 NM_001024457
RGPD1
RANBP2-like and GRIP domain containing 1
chr2_+_161701711 0.176 NM_004180
NM_133484
TANK

TRAF family member-associated NFKB activator

chr19_+_7859380 0.174 NM_025061
LRRC8E
leucine rich repeat containing 8 family, member E
chr1_-_110735158 0.174 NM_004696
SLC16A4
solute carrier family 16, member 4 (monocarboxylic acid transporter 5)
chr1_+_154095883 0.168 NM_152280
SYT11
synaptotagmin XI
chr17_-_33179118 0.168 NM_000458
NM_001165923
HNF1B

HNF1 homeobox B

chr2_+_170074457 0.166 NM_006063
KBTBD10
kelch repeat and BTB (POZ) domain containing 10
chr2_+_73973600 0.166 NM_001615
ACTG2
actin, gamma 2, smooth muscle, enteric
chr3_-_195571748 0.165 NM_001135057
NM_130830
LRRC15

leucine rich repeat containing 15

chr4_-_159312973 0.163 FAM198B
family with sequence similarity 198, member B
chr16_-_21130368 0.162 NM_003460
ZP2
zona pellucida glycoprotein 2 (sperm receptor)
chr6_+_83834080 0.160 NM_015018
DOPEY1
dopey family member 1
chr6_+_25760352 0.159 NM_006998
SCGN
secretagogin, EF-hand calcium binding protein
chr16_-_70763524 0.158 NM_031293
PMFBP1
polyamine modulated factor 1 binding protein 1
chr2_-_254037 0.156 NM_001159597
NM_015677
SH3YL1

SH3 domain containing, Ysc84-like 1 (S. cerevisiae)

chr7_-_50600536 0.155 NM_001082971
DDC
dopa decarboxylase (aromatic L-amino acid decarboxylase)
chr2_+_73973640 0.151 ACTG2
actin, gamma 2, smooth muscle, enteric
chr5_+_140454382 0.149 NM_018936
PCDHB2
protocadherin beta 2
chr6_-_52818851 0.148 NM_153699
GSTA5
glutathione S-transferase alpha 5
chr1_+_150958621 0.146 NM_001024679
C1orf68
chromosome 1 open reading frame 68
chr6_+_64414389 0.144 NM_015153
PHF3
PHD finger protein 3
chr5_+_176806401 0.143 NM_001174101
NM_030567
PRR7

proline rich 7 (synaptic)

chr1_-_229181203 0.140 TTC13
tetratricopeptide repeat domain 13
chr8_+_121526823 0.140 NM_022045
MTBP
Mdm2, transformed 3T3 cell double minute 2, p53 binding protein (mouse) binding protein, 104kDa
chr14_+_23771464 0.140 NM_001002000
NM_001002001
GMPR2

guanosine monophosphate reductase 2

chr9_+_111442888 0.132 NM_001037293
PALM2
paralemmin 2
chr17_+_8154864 0.132 NM_025014
ARHGEF15
Rho guanine nucleotide exchange factor (GEF) 15
chrX_+_105932536 0.128 NM_017752
NM_198881
TBC1D8B

TBC1 domain family, member 8B (with GRAM domain)

chr10_+_42953886 0.127 NM_018590
CSGALNACT2
chondroitin sulfate N-acetylgalactosaminyltransferase 2
chr2_-_253982 0.126 SH3YL1
SH3 domain containing, Ysc84-like 1 (S. cerevisiae)
chr22_+_16423147 0.124 NM_031481
SLC25A18
solute carrier family 25 (mitochondrial carrier), member 18
chr16_-_342399 0.120 NM_003502
NM_181050
AXIN1

axin 1

chr7_-_99115454 0.113 NM_000777
NM_001190484
CYP3A5

cytochrome P450, family 3, subfamily A, polypeptide 5

chr2_+_238432925 0.112 NM_005855
RAMP1
receptor (G protein-coupled) activity modifying protein 1
chr2_-_158439868 0.112 NM_001105
ACVR1
activin A receptor, type I
chr11_+_117680504 0.109 NM_000733
CD3E
CD3e molecule, epsilon (CD3-TCR complex)
chr15_+_97010219 0.109 NM_000875
IGF1R
insulin-like growth factor 1 receptor
chr1_+_117345894 0.108 NM_004258
CD101
CD101 molecule
chr12_-_110378240 0.108


chr5_-_59819642 0.107 NM_001165899
PDE4D
phosphodiesterase 4D, cAMP-specific
chr22_+_19239221 0.107 MED15
mediator complex subunit 15
chr12_-_56200547 0.106 NM_001195053
NM_001195054
NM_001195055
NM_001195056
NM_001195057
NM_004083
DDIT3





DNA-damage-inducible transcript 3





chr9_-_134809816 0.106 NM_000368
NM_001162426
NM_001162427
TSC1


tuberous sclerosis 1


chr12_-_54522881 0.106 NM_002429
MMP19
matrix metallopeptidase 19
chr16_-_52295214 0.105 NM_001127897
NM_015272
RPGRIP1L

RPGRIP1-like

chr11_+_61766299 0.105 NM_006551
SCGB1D2
secretoglobin, family 1D, member 2
chr1_+_158352143 0.104 NM_000702
ATP1A2
ATPase, Na+/K+ transporting, alpha 2 polypeptide
chr2_+_108271526 0.103 NM_001056
NM_176825
SULT1C2

sulfotransferase family, cytosolic, 1C, member 2

chr13_+_51334117 0.103 NM_031290
CCDC70
coiled-coil domain containing 70
chr6_+_88026338 0.102 ZNF292
zinc finger protein 292
chr16_-_29845024 0.101 KCTD13
potassium channel tetramerisation domain containing 13
chr6_+_72982865 0.099 NM_001168409
RIMS1
regulating synaptic membrane exocytosis 1
chr13_+_113023938 0.098 LAMP1
lysosomal-associated membrane protein 1
chr11_+_124984559 0.096 STT3A
STT3, subunit of the oligosaccharyltransferase complex, homolog A (S. cerevisiae)
chr6_+_155579788 0.095 NM_001010927
TIAM2
T-cell lymphoma invasion and metastasis 2
chr1_+_242281175 0.094 NM_205768
ZNF238
zinc finger protein 238
chr14_-_23623657 0.093 NM_006177
NRL
neural retina leucine zipper
chrX_-_24575146 0.091 PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr20_+_35266581 0.090 RPN2
ribophorin II
chr4_+_160408447 0.089 NM_014247
RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
chr10_-_79459296 0.087 NM_007055
POLR3A
polymerase (RNA) III (DNA directed) polypeptide A, 155kDa
chr1_+_27591738 0.086 NM_005281
GPR3
G protein-coupled receptor 3
chr1_+_67404756 0.085 NM_144701
IL23R
interleukin 23 receptor
chr19_+_17527502 0.085 NM_024656
GLT25D1
glycosyltransferase 25 domain containing 1
chr14_+_23527866 0.084 NM_198083
DHRS4
DHRS4L2
dehydrogenase/reductase (SDR family) member 4
dehydrogenase/reductase (SDR family) member 4 like 2

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.76 1.47e-02 GO:0005576 extracellular region

Nothing significant found in function category.